Roxadustat, CAS [[808118-40-3]]

Product Overview

• Article Name: Roxadustat, CAS [[808118-40-3]]
• Biozol Catalog Number: FBM-10-4468
• Supplier Catalog Number: 10-4468
• Alternative Catalog Number: FBM-10-4468-5MG,FBM-10-4468-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: FG-4592

Product Description

Prolyl hydroxylase domain inhibitor / HIF stabilizer

Product Properties

• Molecular Weight: 352.35
• Purity: 99% by HPLC
• Form: Off-white or white solid
• CAS Number: [808118-40-3]
• Formula: C19H16N2O5

Application Notes

• Application Notes: Roxadustat (808118-40-3) is a pan-prolyl hydroxylase domain (PHD) inhibitor (IC50 for PHD2 = 591 nM)1 that stabilizes hypoxia-inducible factor (HIF) leading to erythropoiesis. Currently in clinical trials for treatment of anemia related to chronic kidney