PF-06840003, CAS [[198474-05-4]]

Product Overview

• Article Name: PF-06840003, CAS [[198474-05-4]]
• Biozol Catalog Number: FBM-10-4498
• Supplier Catalog Number: 10-4498
• Alternative Catalog Number: FBM-10-4498-10MG,FBM-10-4498-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: EOS200271

Product Description

IDO1 inhibitor

Product Properties

• Molecular Weight: 232.21
• Purity: 98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [198474-05-4]
• Formula: C12H9FN2O2

Application Notes

• Application Notes: PF-06840003 (198474-05-4) is a potent (IC50 = 150 and 410 nM via two methods) and selective inhibitor of Indoleamine-2,3-dioxygenase (IDO1).1 In mice with syngeneic tumor grafts, it reduced intratumoral kynurenine levels by over 80%, inhibited tumor grow