PF-06840003, CAS [[198474-05-4]]

Catalog Number: FBM-10-4498
Article Name: PF-06840003, CAS [[198474-05-4]]
Biozol Catalog Number: FBM-10-4498
Supplier Catalog Number: 10-4498
Alternative Catalog Number: FBM-10-4498-10MG,FBM-10-4498-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: EOS200271
IDO1 inhibitor
Molecular Weight: 232.21
Purity: 98% by TLC NMR (Conforms)
Form: White solid
CAS Number: [198474-05-4]
Formula: C12H9FN2O2
Application Notes: PF-06840003 (198474-05-4) is a potent (IC50 = 150 and 410 nM via two methods) and selective inhibitor of Indoleamine-2,3-dioxygenase (IDO1).1 In mice with syngeneic tumor grafts, it reduced intratumoral kynurenine levels by over 80%, inhibited tumor grow