98% by TLC [Pyridine/HOAc/H2O/n-Butanol 1:2:2:6, Rf = 0.30] NMR (conforms)
Form:
White solid
CAS Number:
[214358-33-5]
Formula:
C10H15N3 2HCl
Application Notes:
Potent, tight-binding, slow inhibitor of inducible nitric oxide synthase (iNOS). Highly selective for iNOS3 (Ki = 7 nM) over nNOS or eNOS (Kis of 2 µM and 50 µM respectively).1 Cell permeable and active in vivo.2
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