AZD6244, CAS [[606143-52-6]]

Product Overview

• Article Name: AZD6244, CAS [[606143-52-6]]
• Biozol Catalog Number: FBM-10-4509
• Supplier Catalog Number: 10-4509
• Alternative Catalog Number: FBM-10-4509-10MG,FBM-10-4509-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: ARRY-142886, Selumetinib

Product Description

ERK inhibitor

Product Properties

• Molecular Weight: 457.68
• Purity: 99% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [606143-52-6]
• Formula: C17H15BrClFN4O3

Application Notes

• Application Notes: AZD6244 is a potent, selective, and non-ATP competitive inhibitor of MEK1/2 (IC50 MEK1 = 14 nM) and ERK 1/2 phosphorylation (IC50 = 10 nM).1,2 AZD 6244 is in clinical trials for treating various cancers.3-7