Ruxolitinib, CAS [[941678-49-5]]

Product Overview

• Article Name: Ruxolitinib, CAS [[941678-49-5]]
• Biozol Catalog Number: FBM-10-4511
• Supplier Catalog Number: 10-4511
• Alternative Catalog Number: FBM-10-4511-5MG,FBM-10-4511-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: INCB 018424

Product Description

JAK inhibitor

Product Properties

• Molecular Weight: 306.37
• Purity: 99% by HPLC, NMR (conforms)
• Form: White solid
• CAS Number: [941678-49-5]
• Formula: C17H18N6

Application Notes

• Application Notes: Potent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cel