98% by TLC [10% ethyl acetate in hexanes / Rf: 0.32] NMR (Conforms)
Form:
White solid
CAS Number:
[357649-93-5]
Formula:
C14H14ClN3S
Application Notes:
CPTH2 is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.8 mM). In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. Its in vivo activity may involve more hist
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