UNC1999, CAS [[1431612-23-5]]

Product Overview

• Article Name: UNC1999, CAS [[1431612-23-5]]
• Biozol Catalog Number: FBM-10-4542
• Supplier Catalog Number: 10-4542
• Alternative Catalog Number: FBM-10-4542-5MG,FBM-10-4542-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Methyltransferase inhibitor

Product Properties

• Molecular Weight: 569.74
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1431612-23-5]
• Formula: C33H43N7O2

Application Notes

• Application Notes: UNC1999 is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50s = 45 nM and 2 nM respectively).1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib in suppressing