SHP099, CAS [[1801747-42-1]]

Catalog Number: FBM-10-4604
Article Name: SHP099, CAS [[1801747-42-1]]
Biozol Catalog Number: FBM-10-4604
Supplier Catalog Number: 10-4604
Alternative Catalog Number: FBM-10-4604-5MG,FBM-10-4604-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
SHP2 inhibitor
Molecular Weight: 352.27
Purity: 98% by HPLC, NMR (Conforms)
Form: Yellow solid
CAS Number: [1801747-42-1]
Formula: C16H19Cl2N5
Application Notes: SHP099 is a potent (IC50 = 71 nM) and selective allosteric inhibitor of SHP2. SHP2 is a non-receptor tyrosine phosphatase that regulates cell survival and proliferation through activating the RAS-ERK pathway. It also mediates programmed cell death 1 (PD-