TH1760, CAS [[2567914-01-4]]

Product Overview

• Article Name: TH1760, CAS [[2567914-01-4]]
• Biozol Catalog Number: FBM-10-4624
• Supplier Catalog Number: 10-4624
• Alternative Catalog Number: FBM-10-4624-5MG,FBM-10-4624-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

NUDT15 inhibitor

Product Properties

• Molecular Weight: 426.45
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [2567914-01-4]
• Formula: C20H18N4O5S

Application Notes

• Application Notes: Potent inhibitor (IC50 = 25 nM dGTP hydrolysis, 57 nM 6-thio-dGTP hydrolysis) of the NUDIX hydrolase NUDT15, an important enzyme involved in the hydrolysis thiopurine chemotherapeutics. It was selective against other human NUDIX proteins as well as a pan