VU0134992, CAS [[755002-90-5]]

Product Overview

• Article Name: VU0134992, CAS [[755002-90-5]]
• Biozol Catalog Number: FBM-10-4651
• Supplier Catalog Number: 10-4651
• Alternative Catalog Number: FBM-10-4651-5MG,FBM-10-4651-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Kir4.1 blocker

Product Properties

• Molecular Weight: 411.38
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white/tan solid
• CAS Number: [755002-90-5]
• Formula: C20H31BrN2O2

Application Notes

• Application Notes: VU0134992 is a blocker of the inward rectifier potassium channel Kir4.1 (IC50 = 970 nM).1 It also inhibits Kir3.1/3.2, Kir3.1/3.4, and Kir4.2 with similar potency. VU0134992 induced diuresis, natriuresis, and kaliuresis in Sprague-Dawley rats suggesting