Vorasidenib, CAS [[1644545-52-7]]

Product Overview

• Article Name: Vorasidenib, CAS [[1644545-52-7]]
• Biozol Catalog Number: FBM-10-4659
• Supplier Catalog Number: 10-4659
• Alternative Catalog Number: FBM-10-4659-5MG,FBM-10-4659-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AG-881

Product Description

Isocitrate dehydrogenase (IDH) 1/2 inhibitor

Product Properties

• Molecular Weight: 414.74
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1644545-52-7]
• Formula: C14H13ClF6N6

Application Notes

• Application Notes: Vorasidenib is a highly potent (IC50s = 7 nM IDH2-R140Q, 0.6 nM IDH1-R132H/WT, and 0.25 nM Neurosphere TS603 IDH1-R132H), selective, and brain-penetrant inhibitor of mutant isocitrate dehydrogenase 1 and 2 (IDH1/2).1 It led to >97% inhibition of 2-hydro