PB28 dihydrochloride, CAS [[172907-03-8]]

Product Overview

• Article Name: PB28 dihydrochloride, CAS [[172907-03-8]]
• Biozol Catalog Number: FBM-10-4665
• Supplier Catalog Number: 10-4665
• Alternative Catalog Number: FBM-10-4665-5MG,FBM-10-4665-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

High affinity sigma 2 ligand / Anti-SARS-COV2

Product Properties

• Molecular Weight: 443.50
• Purity: 99% by HPLC NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [172907-03-8]
• Formula: C24H38N2O2HCl

Application Notes

• Application Notes: PB28 is a very potent high affinity (Ki = 5.3 nM1, 0.34 nM2) sigma 2 agonist. Selective for sigma 2 over sigma1 (approx 30-40x).1,2 PB28 inhibited cell growth in MCF7 and MCF7 ADR breast cancer cells and displayed strong synergism with doxorubicin.3 PB28