R428, CAS [[1037624-75-1]]

Product Overview

• Article Name: R428, CAS [[1037624-75-1]]
• Biozol Catalog Number: FBM-10-4676
• Supplier Catalog Number: 10-4676
• Alternative Catalog Number: FBM-10-4676-5MG,FBM-10-4676-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Bemcentinib, BGB324

Product Description

AXL inhibitor

Product Properties

• Molecular Weight: 506.64
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [1037624-75-1]
• Formula: C30H34N8

Application Notes

• Application Notes: R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and func