Rebastinib, CAS [[1020172-07-9]]

Product Overview

• Article Name: Rebastinib, CAS [[1020172-07-9]]
• Biozol Catalog Number: FBM-10-4689
• Supplier Catalog Number: 10-4689
• Alternative Catalog Number: FBM-10-4689-5MG,FBM-10-4689-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: DCC-2036

Product Description

Bcl-Abl1 inhibitor

Product Properties

• Molecular Weight: 553.6
• Purity: >98% by HPLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [1020172-07-9]
• Formula: C30H28FN7O6

Application Notes

• Application Notes: Rebastinib is a potent ABL1 kinase inhibitor (IC50 = 0.8 nM) that binds to amino acid residues that are used to switch between active and inactive conformations.1 It inhibits both phosphorylated and unphosphorylated ABL1 as well as gatekeeper mutant T315