Glumetinib, CAS [[1642581-63-2]]

Product Overview

• Article Name: Glumetinib, CAS [[1642581-63-2]]
• Biozol Catalog Number: FBM-10-4690
• Supplier Catalog Number: 10-4690
• Alternative Catalog Number: FBM-10-4690-5MG,FBM-10-4690-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: SCC244

Product Description

Highly selective c-Met inhibitor

Product Properties

• Molecular Weight: 459.48
• Purity: 98% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [1642581-63-2]
• Formula: C21H17N9O2S

Application Notes

• Application Notes: Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.