JH-X-119-01, CAS [[2227368-54-7]]

Product Overview

• Article Name: JH-X-119-01, CAS [[2227368-54-7]]
• Biozol Catalog Number: FBM-10-4691
• Supplier Catalog Number: 10-4691
• Alternative Catalog Number: FBM-10-4691-5MG,FBM-10-4691-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: N-[4-[[3-(Prop-2-enoylamino)benzoyl]amino]phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide

Product Description

Selective IRAK1 inhibitor

Product Properties

• Molecular Weight: 452.47
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [2227368-54-7]
• Formula: C25H20N6O3

Application Notes

• Application Notes: JH-X-119-01 is a highly selective (significantly inhibited only YSK4 and MEK3 in a panel of over 300 kinases) and potent (IC50 = 9 nM) covalent inhibitor of interleukin 1 receptor-associated kinase 1 (IRAK1). It displayed cytotoxic activity against sever