GSK8612, CAS [[2361659-62-1]]

Product Overview

• Article Name: GSK8612, CAS [[2361659-62-1]]
• Biozol Catalog Number: FBM-10-4693
• Supplier Catalog Number: 10-4693
• Alternative Catalog Number: FBM-10-4693-5MG,FBM-10-4693-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Highly selective TBK1 inhibitor

Product Properties

• Molecular Weight: 520.33
• Purity: 98% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [2361659-62-1]
• Formula: C17H17BrF3N7O2S

Application Notes

• Application Notes: Highly selective and potent (avg. pIC50 = 6.8 versus recombinant TBK1) inhibitor of Tank-binding Kinase-1 (TBK1) with higher affinity for unactivated TBK1. It inhibited phosphorylation of IRF3 (pIC50 = 6.0), inhibited the release of IFNa from human PBMC