BAY-876, CAS [[1799753-84-6]]

Product Overview

• Article Name: BAY-876, CAS [[1799753-84-6]]
• Biozol Catalog Number: FBM-10-4708
• Supplier Catalog Number: 10-4708
• Alternative Catalog Number: FBM-10-4708-5MG,FBM-10-4708-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: 4-N-[1-[(4-Cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide

Product Description

GLUT1 inhibitor

Product Properties

• Molecular Weight: 496.43
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1799753-84-6]
• Formula: C24H16F4N6O2

Application Notes

• Application Notes: Potent inhibitor (IC50 = 2 nM) of the facilitative glucose transporter GLUT1, an enzyme frequently overexpressed in many cancers.1 It shows greater than 100-fold selectivity over GLUT2-4. BAY-876 displayed potent antitumor activity in ovarian cancer xeno