PLX5622, CAS [[1303420-67-8]]

Product Overview

• Article Name: PLX5622, CAS [[1303420-67-8]]
• Biozol Catalog Number: FBM-10-4726
• Supplier Catalog Number: 10-4726
• Alternative Catalog Number: FBM-10-4726-5MG,FBM-10-4726-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Highly selective CSF1R inhibitor

Product Properties

• Molecular Weight: 395.41
• Purity: 98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [1303420-67-8]
• Formula: C21H19F2N5O

Application Notes

• Application Notes: Highly selective (>20 fold over KIT and FLT3, >60 fold over 200 other kinases) and brain-penetrant inhibitor of colony-stimulating factor 1 receptor (CSF1R, IC50 = 16 nM).1 It prevented plaque formation in 5xFAD1 and 3xTg2 mouse models of Alzheimers dis