Palbociclib, CAS [[571190-30-2]]

Product Overview

• Article Name: Palbociclib, CAS [[571190-30-2]]
• Biozol Catalog Number: FBM-10-4760
• Supplier Catalog Number: 10-4760
• Alternative Catalog Number: FBM-10-4760-5MG,FBM-10-4760-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: PD-332991, PD0332991

Product Description

CDK4/CDK6 inhibitor

Product Properties

• Molecular Weight: 447.53
• Purity: 99% by HPLC/TLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [571190-30-2]
• Formula: C24H29N7O2

Application Notes

• Application Notes: Potent and selective inhibitor of Cdk4, IC50 = 11 nM and Cdk6, IC50 = 16 nM.1 Inhibits phosphorylation of Rb protein and cell cycle progression through G1 in primary 5T33MM cells and sensitized these cells to killing by a proteasome inhibitor (bortezomib