LDN-193189 HCl, CAS [[1062368-62-0]]

Product Overview

• Article Name: LDN-193189 HCl, CAS [[1062368-62-0]]
• Biozol Catalog Number: FBM-10-4764
• Supplier Catalog Number: 10-4764
• Alternative Catalog Number: FBM-10-4764-5MG,FBM-10-4764-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: DM-3189

Product Description

ALK2 / ALK3 inhibitor

Product Properties

• Molecular Weight: 479.4
• Purity: 99% by HPLC (Agilent Poroshell 120 C18, 80/20 MeOH/water with 0.05% TFA, 0.8 ml/min) NMR (Conforms)
• Form: Orange-yellow solid
• CAS Number: [1062368-62-0]
• Formula: C25H22N62HCl

Application Notes

• Application Notes: LDN-193189 HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripot