IPA-3, CAS [[42521-82-4]]

Product Overview

• Article Name: IPA-3, CAS [[42521-82-4]]
• Biozol Catalog Number: FBM-10-4765
• Supplier Catalog Number: 10-4765
• Alternative Catalog Number: FBM-10-4765-10MG,FBM-10-4765-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PAK1 inhibitor

Product Properties

• Molecular Weight: 350.45
• Purity: 98% by TLC (methylene chloride, Rf=0.75) NMr (Conforms)
• Form: Yellow solid
• CAS Number: [42521-82-4]
• Formula: C20H14O2S2

Application Notes

• Application Notes: IPA-3 is a selective allosteric inhibitor of Group 1 p21-activated kinase (PAK1 IC50 = 2.5 µM)1 via covalent binding to the PAK1 regulatory domain preventing binding to the upstream activator Cdc422. IPA-3 has been shown to induce cell death in human leu