JNK-IN-8, CAS [[1410880-22-6]]

Product Overview

• Article Name: JNK-IN-8, CAS [[1410880-22-6]]
• Biozol Catalog Number: FBM-10-4780
• Supplier Catalog Number: 10-4780
• Alternative Catalog Number: FBM-10-4780-5MG,FBM-10-4780-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: JNK Inhibitor XVI

Product Description

JNK inhibitor

Product Properties

• Molecular Weight: 507.6
• Purity: >98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [1410880-22-6]
• Formula: C29H29N7O2

Application Notes

• Application Notes: JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cogn