BI-D1870 is an inhibitor of p90 ribosomal S6 kinase (RSK, IC50s = RSK1, 31 nM, RSK2, 24 nM, RSK3, 18 nM, RSK4, 15 nM) with selectivity over other AGC kinases.1 It protected mice from experimental autoimmune encephalomyelitis suggesting a new strategy to
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