MTX-531, CAS [[2791417-66-6]]
Catalog Number:
FBM-10-4802
| Article Name: |
MTX-531, CAS [[2791417-66-6]] |
| Biozol Catalog Number: |
FBM-10-4802 |
| Supplier Catalog Number: |
10-4802 |
| Alternative Catalog Number: |
FBM-10-4802-5MG,FBM-10-4802-25MG |
| Manufacturer: |
Focus Biomolecules |
| Category: |
Biochemikalien |
| Molecular Weight: |
453.95 |
| Purity: |
>98% by HPLC NMR (Conforms) |
| Form: |
White solid |
| CAS Number: |
[2791417-66-6] |
| Formula: |
C22H20ClN5O2S |
| Application Notes: |
MTX-531 is a first-in-class dual EGFR/pan-PI3K inhibitor (IC50s: EGFR = 14.7 nM, PI3kalpha = 6.4 nM, PI3Kß = 233 nM, PI3Kgamma = 8.3 nM, PI3Kdelta = 1.1 nM, mTOR = 105 nM, DNA-PK = 5.4 nM). MTX-531 displayed exquisite selectivity for EGFR and PI3K family members (ag |
