Volasertib, CAS [[755038-65-4]]

Product Overview

• Article Name: Volasertib, CAS [[755038-65-4]]
• Biozol Catalog Number: FBM-10-4818
• Supplier Catalog Number: 10-4818
• Alternative Catalog Number: FBM-10-4818-5MG,FBM-10-4818-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: BI 6727

Product Description

Polo-like Kinase 1 inhibitor

Product Properties

• Molecular Weight: 618.82
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [755038-65-4]
• Formula: C34H50N8O3

Application Notes

• Application Notes: Volasertib is an extremely potent and selective inhibitor (IC50s: Plk1= 0.87 nM, Plk2 = 5 nM, Plk3 = 56 nM) of Polo-like kinase 1, a critical controller of multiple essential steps of mitosis.1 It has shown efficacy in multiple solid xenograft tumors mo