Pexidartinib, CAS [[1029044-16-3]]

Product Overview

• Article Name: Pexidartinib, CAS [[1029044-16-3]]
• Biozol Catalog Number: FBM-10-4829
• Supplier Catalog Number: 10-4829
• Alternative Catalog Number: FBM-10-4829-5MG,FBM-10-4829-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: PLX3397

Product Description

CSF1R inhibitor

Product Properties

• Molecular Weight: 417.81
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1029044-16-3]
• Formula: C20H15ClF3N5

Application Notes

• Application Notes: Pexidartinib (1029044-16-3) is a potent and selective dual inhibitor of CSF1R (IC50 = 20nM) and c-KIT (IC50 = 10nM).1 Inhibition of CSF1R with Pexidartinib resulted in a reprogrammed immune microenvironment that fosters antitumor immunity in a CD8+ T-cel