WP1066, CAS [[857064-38-1]]

Product Overview

• Article Name: WP1066, CAS [[857064-38-1]]
• Biozol Catalog Number: FBM-10-4831
• Supplier Catalog Number: 10-4831
• Alternative Catalog Number: FBM-10-4831-10MG,FBM-10-4831-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

JAK/STAT3 inhibitor

Product Properties

• Molecular Weight: 356.22
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [857064-38-1]
• Formula: C17H14BrN3O

Application Notes

• Application Notes: WP1066 (857064-38-1) is an inhibitor of the JAK2/STAT3 pathway as well as STAT5 and AKT.1,2,3 It downregulated Bcl-XL, Mcl-1, and c-myc while activating Bax and inducing apoptosis.1 Active against human malignant glioma U87-MG (IC50 = 5.6µM) and U373-MG