Larotrectinib, CAS [[1223403-58-4]]

Catalog Number: FBM-10-4832
Article Name: Larotrectinib, CAS [[1223403-58-4]]
Biozol Catalog Number: FBM-10-4832
Supplier Catalog Number: 10-4832
Alternative Catalog Number: FBM-10-4832-5MG,FBM-10-4832-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: LOXO-101, ARRY-470
panTRK inhibitor
Molecular Weight: 428.44
Purity: 98% by HPLC NMR (Conforms)
Form: Yellow solid
CAS Number: [1223403-58-4]
Formula: C21H22F2N6O2
Application Notes: Larotrectinib is a potent (IC50s < 11 nM) inhibitor of tropomyosin receptor kinases A, B, and C (TrkA, B, and C).1 It is >100 fold selective against a panel of 229 kinases. Larotrectinib markedly attenuated bone cancer pain and significantly blocked the