RK-33, CAS [[1070773-09-9]]

Product Overview

• Article Name: RK-33, CAS [[1070773-09-9]]
• Biozol Catalog Number: FBM-10-4839
• Supplier Catalog Number: 10-4839
• Alternative Catalog Number: FBM-10-4839-5MG,FBM-10-4839-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

DDX3 inhibitor

Product Properties

• Molecular Weight: 428.44
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [1070773-09-9]
• Formula: C23H20N6O3

Application Notes

• Application Notes: RK-33 is an inhibitor of the RNA helicase DDX3 - IC50s = 4.4-8.4 µM in high DDX3 expressing lung cancer cell lines A549, H1299, H23, and H460.1,2 Inhibition of DDX3 led to activation of cell death pathways, inhibition of Wnt pathway signaling, and abrog