NDI-091143, CAS [[2375840-87-0]]
Catalog Number:
FBM-10-4841
Article Name: |
NDI-091143, CAS [[2375840-87-0]] |
Biozol Catalog Number: |
FBM-10-4841 |
Supplier Catalog Number: |
10-4841 |
Alternative Catalog Number: |
FBM-10-4841-5MG,FBM-10-4841-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Potent allosteric ATP-citrate lyase inhibitor |
Molecular Weight: |
453.84 |
Purity: |
>98% by HPLC NMR (Conforms) |
Form: |
Off-white solid |
CAS Number: |
[2375840-87-0] |
Formula: |
C20H14ClF2NO5S |
Application Notes: |
Potent (IC50 = 2.1 nM ADP-Glo assay, 4.8 nM Oxaloacetate coupled enzyme assay) allosteric inhibitor of ATP-citrate lyase.1 NDI-091143 suppressed growth and clonogenic ability in thyroid cancer cell lines FTC-133 and 8505C.2 It also synergistically potent |