JTE-607, CAS [[188791-09-5]]
Catalog Number:
FBM-10-4842
Article Name: |
JTE-607, CAS [[188791-09-5]] |
Biozol Catalog Number: |
FBM-10-4842 |
Supplier Catalog Number: |
10-4842 |
Alternative Catalog Number: |
FBM-10-4842-5MG,FBM-10-4842-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
mRNA processing inhibitor |
Molecular Weight: |
597.36 |
Purity: |
98% by HPLC NMR (Conforms) |
Form: |
White solid |
CAS Number: |
[188791-09-5] |
Formula: |
C25H31Cl2N3O52HCl |
Application Notes: |
JTE-607 inhibits inflammatory cytokine production in human peripheral blood mononuclear cells (PBMCs) without causing immunosuppression: IC50s = 11 nM (TNF-), 5.9 nM (IL-1), 8.8 nM (IL-6), 7.3 nM (IL-8), and 9.1 nM (IL-10).1 It displayed efficacy in |