LY2090314, CAS [[603288-22-8]]

Product Overview

• Article Name: LY2090314, CAS [[603288-22-8]]
• Biozol Catalog Number: FBM-10-4854
• Supplier Catalog Number: 10-4854
• Alternative Catalog Number: FBM-10-4854-5MG,FBM-10-4854-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: 3-(9-Fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6.7.1-hi]indol-7-yl)-4-(imidazo[1.2-a]pyridine-3-yl)-1H-pyrrole-2,5-dione

Product Description

Wnt/ß-Catenin pathway activator / GSK-3 inhibitor

Product Properties

• Molecular Weight: 512.54
• Purity: >98% by HPLC NMR (Conforms)
• Form: Orange solid
• CAS Number: [603288-22-8]
• Formula: C28H25FN6O3

Application Notes

• Application Notes: Wnt/ß-catenin pathway activator. LY2090314 is a highly potent (IC50 = 1.5 nM GSK-3alpha, 0.9 nM GSK-3ß) and selective inhibitor of glycogen synthase-3-kinase (GSK-3).1,2 It stabilized ß-catenin levels and elevated expression of Axin2 leading to tumor growth