GSK872, CAS [[1346546-69-7]]

Product Overview

• Article Name: GSK872, CAS [[1346546-69-7]]
• Biozol Catalog Number: FBM-10-4861
• Supplier Catalog Number: 10-4861
• Alternative Catalog Number: FBM-10-4861-5MG,FBM-10-4861-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GSK2399872A, GSK872

Product Description

Necroptosis inhibitor / RIP3 inhibitor

Product Properties

• Molecular Weight: 383.49
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white or pale yellow solid
• CAS Number: [1346546-69-7]
• Formula: C19H17N3O2S2

Application Notes

• Application Notes: GSK872 is a potent (IC50 = 1.8nM domain binding, IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce