LD2, CAS [[1134334-55-6]]

Product Overview

• Article Name: LD2, CAS [[1134334-55-6]]
• Biozol Catalog Number: FBM-10-4872
• Supplier Catalog Number: 10-4872
• Alternative Catalog Number: FBM-10-4872-5MG,FBM-10-4872-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PRMT9 inhibitor

Product Properties

• Molecular Weight: 247.68
• Purity: >98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [1134334-55-6]
• Formula: C12H10ClN3O

Application Notes

• Application Notes: LD2 is a protein arginine N-methyltransferase 9 (PRMT9) inhibitor. It inhibited the viability of leukemia cells (IC50 = 2-7 µM in various cell lines). LD2 promoted DNA damage leading to cyclic GMP-AMP synthase (cGAS) activation and a type I IFN response.