Selectively induces apoptosis in cells with APC truncations
Molecular Weight:
388.95
Purity:
98% by HPLC NMR (Conforms)
Form:
White or off-white solid
CAS Number:
[1678515-13-3]
Formula:
C18H28N2O3SHCl
Application Notes:
Selectively induces apoptosis in cells with truncations in the adenomatous polyposis coli (APC) gene (but not normal cells or wild type cancer cells), an important multifunctional tumor suppressor gene.1 IC50 = 70nM for DLD1 cell line. It inhibited cance
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