BAY 87-2243, CAS [[1227158-85-1]]

Product Overview

• Article Name: BAY 87-2243, CAS [[1227158-85-1]]
• Biozol Catalog Number: FBM-10-4910
• Supplier Catalog Number: 10-4910
• Alternative Catalog Number: FBM-10-4910-5MG,FBM-10-4910-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

HIF-1 / Mitochondrial complex I inhibitor

Product Properties

• Molecular Weight: 525.54
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1227158-85-1]
• Formula: C26H26F3N7O2

Application Notes

• Application Notes: BAY 87-2243 potently inhibits HIF-1 reporter gene activity (IC50 = 0.7 nM) and CA9 protein expression (IC50 = 2.0 nM).1 It inhibited HIF-1 and HIF-2 protein accumulation in hypoxic H460 cells and reduced tumor weight in nude mice inoculated with H460 c