ML792, CAS [[1644342-14-2]]

Product Overview

• Article Name: ML792, CAS [[1644342-14-2]]
• Biozol Catalog Number: FBM-10-4985
• Supplier Catalog Number: 10-4985
• Alternative Catalog Number: FBM-10-4985-5MG,FBM-10-4985-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

SUMO-activating enzyme (SAE) inhibitor

Product Properties

• Molecular Weight: 551.42
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1644342-14-2]
• Formula: C21H23BrN6O5S

Application Notes

• Application Notes: ML792 is a potent (IC50s = 3 nM SUMO1, 11 nM SUMO2) and selective( IC50 = 32 µM for NEDD8-activating enzyme (NAE)) mechanism-based inhibitor of SUMO-activating enzyme (SAE).1 Treatment of multiple cancer cell lines led to failure of mitotic progression