PF-543 HCl, CAS [[1706522-79-3]]

Product Overview

• Article Name: PF-543 HCl, CAS [[1706522-79-3]]
• Biozol Catalog Number: FBM-10-4998
• Supplier Catalog Number: 10-4998
• Alternative Catalog Number: FBM-10-4998-5MG,FBM-10-4998-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Sphingosine kinase-1 inhibitor

Product Properties

• Molecular Weight: 502.07
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1706522-79-3]
• Formula: C27H31NO4SHCl

Application Notes

• Application Notes: PF-543 (1706522-79-3) is a potent (IC50 = 2.0 nM) and selective (>100-fold over SphK2) reversible inhibitor of sphingosine kinase-1 (SphK1).1 It induced autophagy in head and neck squamous cell carcinoma cells.2 PF-543 mitigated pulmonary fibrosis via re