Osimertinib, CAS [[1421373-65-0]]

Product Overview

• Article Name: Osimertinib, CAS [[1421373-65-0]]
• Biozol Catalog Number: FBM-10-5036
• Supplier Catalog Number: 10-5036
• Alternative Catalog Number: FBM-10-5036-10MG,FBM-10-5036-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AZD-9291

Product Description

Mutant EGFR kinase inhibitor

Product Properties

• Molecular Weight: 499.62
• Purity: >98% by HPLC NMR (Conforms)
• Form: Pale-yellow solid
• CAS Number: [1421373-65-0]
• Formula: C28H33N7O2

Application Notes

• Application Notes: Osimertinib is a potent, selective, irreversible inhibitor of mutant EFGR tyrosine kinase.1 Osimertinib inhibits phosphorylation of EGFR in T790M-mutant cell lines (IC50 <15 nM) but was less potent at inhibition of EGFR phosphorylation in wild-type cells