GKT-137831, CAS [[1218942-37-0]]

Catalog Number: FBM-10-5044
Article Name: GKT-137831, CAS [[1218942-37-0]]
Biozol Catalog Number: FBM-10-5044
Supplier Catalog Number: 10-5044
Alternative Catalog Number: FBM-10-5044-5MG,FBM-10-5044-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Setanaxib, GKT-831
NADPH oxidase NOX1/4 inhibitor
Molecular Weight: 394.85
Purity: 98% by TLC NMR (Conforms)
Form: Pale-yellow solid
CAS Number: [1218942-37-0]
Formula: C21H19ClN4O2
Application Notes: NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in