GKT-137831, CAS [[1218942-37-0]]
Catalog Number:
FBM-10-5044
Article Name: |
GKT-137831, CAS [[1218942-37-0]] |
Biozol Catalog Number: |
FBM-10-5044 |
Supplier Catalog Number: |
10-5044 |
Alternative Catalog Number: |
FBM-10-5044-5MG,FBM-10-5044-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Alternative Names: |
Setanaxib, GKT-831 |
NADPH oxidase NOX1/4 inhibitor |
Molecular Weight: |
394.85 |
Purity: |
98% by TLC NMR (Conforms) |
Form: |
Pale-yellow solid |
CAS Number: |
[1218942-37-0] |
Formula: |
C21H19ClN4O2 |
Application Notes: |
NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in |