Ponatinib, CAS [[943319-70-8]]

Product Overview

• Article Name: Ponatinib, CAS [[943319-70-8]]
• Biozol Catalog Number: FBM-10-5064
• Supplier Catalog Number: 10-5064
• Alternative Catalog Number: FBM-10-5064-5MG,FBM-10-5064-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AP-24534

Product Description

Bcr-Abl and multikinase inhibitor

Product Properties

• Molecular Weight: 532.56
• Purity: 98% by HPLC NMR (Conforms)
• Form: yellow solid
• CAS Number: [943319-70-8]
• Formula: C29H27F3N6O

Application Notes

• Application Notes: Highly potent pan-Bcr-Abl and multikinase inhibitor, suppressing the activity of native Bcr-Abl (IC50=0.37 nM) as well as the mutants T315I (IC50=2 nM), Q252H (IC50=0.44 nM), Y253F (IC50=0.3 nM), M351T (IC50=0.3 nM) and H396P (IC50=0.34 nM).1 Also inhibi