ML133 HCl, CAS [[1222781-70-5]]

Product Overview

• Article Name: ML133 HCl, CAS [[1222781-70-5]]
• Biozol Catalog Number: FBM-10-5098
• Supplier Catalog Number: 10-5098
• Alternative Catalog Number: FBM-10-5098-5MG,FBM-10-5098-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Kir2 potassium channel blocker

Product Properties

• Molecular Weight: 313.83
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1222781-70-5]
• Formula: C19H19NO HCl

Application Notes

• Application Notes: ML133 is a potent and selective blocker of the inwardly rectifying Kir2 potassium channel, IC50s = 1.8, 2.8, 2,9, and 4.0 µM for Kir2.1, Kir2.6, Kir2.2, and Kir2.3, respectively.1 Intrathecal injection of ML133 attenuated the proliferation of microglia a