ML133 HCl, CAS [[1222781-70-5]]

Catalog Number: FBM-10-5098
Article Name: ML133 HCl, CAS [[1222781-70-5]]
Biozol Catalog Number: FBM-10-5098
Supplier Catalog Number: 10-5098
Alternative Catalog Number: FBM-10-5098-5MG, FBM-10-5098-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Kir2 potassium channel blocker
Molecular Weight: 313.83
Purity: >98% by HPLC NMR (Conforms)
Form: White solid
CAS Number: [1222781-70-5]
Formula: C19H19NO HCl
Application Notes: ML133 is a potent and selective blocker of the inwardly rectifying Kir2 potassium channel, IC50s = 1.8, 2.8, 2,9, and 4.0 µM for Kir2.1, Kir2.6, Kir2.2, and Kir2.3, respectively.1 Intrathecal injection of ML133 attenuated the proliferation of microglia a