PLX4720, CAS [[918505-84-7]]

Catalog Number: FBM-10-5113
Article Name: PLX4720, CAS [[918505-84-7]]
Biozol Catalog Number: FBM-10-5113
Supplier Catalog Number: 10-5113
Alternative Catalog Number: FBM-10-5113-5MG,FBM-10-5113-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Mutant B-Raf inhibitor
Molecular Weight: 413.82
Purity: >98% by HPLC NMR (Conforms)
Form: White solid
CAS Number: [918505-84-7]
Formula: C17H14ClF2N3O3S
Application Notes: Potent and selective inhibitor of B-Raf, V600E mutant, IC50=13 nM (Wild type IC50=160 nM).1 It induces cell cycle arrest and apoptosis in B-RafV600E-positive cells and suppresses growth of B-RafV600E-positive xenografts.1 It induces tumor regression and