SM-164, CAS [[957135-43-2]]

Product Overview

• Article Name: SM-164, CAS [[957135-43-2]]
• Biozol Catalog Number: FBM-10-5464
• Supplier Catalog Number: 10-5464
• Alternative Catalog Number: FBM-10-5464-1MG,FBM-10-5464-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Smac mimetic

Product Properties

• Molecular Weight: 1121.45
• Purity: 98% by HPLC NMR (Conforms)
• Form: White to pale-yellow solid
• CAS Number: [957135-43-2]
• Formula: C62H84N14O6

Application Notes

• Application Notes: Cell-permeable Smac (DIABLO) mimetic that inhibits caspase blockers XIAP, cIAP1, and cIAP2 (Ki = 36, <1, and <1.9 nM), thus inducing apoptosis.1-3 SM-164 sensitizes cancer cells to DNA damaging agents.4 It also prevents binding of Hsp70 to XIAP.5 At high