SGI-1027, CAS [[1020149-73-8]]

Product Overview

• Article Name: SGI-1027, CAS [[1020149-73-8]]
• Biozol Catalog Number: FBM-10-5488
• Supplier Catalog Number: 10-5488
• Alternative Catalog Number: FBM-10-5488-5MG,FBM-10-5488-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

DNA methyl transferase inhibitor

Product Properties

• Molecular Weight: 451.52
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1020149-73-8]
• Formula: C27H23N7O

Application Notes

• Application Notes: Potent and selective inhibitor of DNA methyl transferase inhibiting DNMT1, DNMT3A and DNMT3B with comparable potency (IC50=12.5, 8.0 and 7.5 M respectively).1 Treatment of various cancer cell lines with SGI-1027 results in selective degradation of DNMT1