Pyridone 6, CAS [[457081-03-7]]

Product Overview

• Article Name: Pyridone 6, CAS [[457081-03-7]]
• Biozol Catalog Number: FBM-10-5555
• Supplier Catalog Number: 10-5555
• Alternative Catalog Number: FBM-10-5555-1MG,FBM-10-5555-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: JAK Inhibitor I

Product Description

pan-JAK inhibitor

Product Properties

• Molecular Weight: 309.34
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [457081-03-7]
• Formula: C18H16FN3O

Application Notes

• Application Notes: Potent, ATP-competitive pan-JAK inhibitor. Inhibits 1, 2 and 3 (IC50=1, 5 and 15 nM respectively) as well as JAK family member Tyk2 (IC50=1 nM).1 Also tested against 21 other kinases with inhibition ranging from 130 nm to >10 mM. Inhibits IL2 and IL4-dep