TPCA-1, CAS [[507475-17-4]]

Product Overview

• Article Name: TPCA-1, CAS [[507475-17-4]]
• Biozol Catalog Number: FBM-10-5571
• Supplier Catalog Number: 10-5571
• Alternative Catalog Number: FBM-10-5571-5MG,FBM-10-5571-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Selective inhibitor of IkappaB kinase 2 (IKK2)

Product Properties

• Molecular Weight: 229.29
• Purity: 98% by TLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [507475-17-4]
• Formula: C12H10FN3O4S

Application Notes

• Application Notes: Selective inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 17.9 nM).1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses