BMH-21, CAS [[896705-16-1]]

Product Overview

• Article Name: BMH-21, CAS [[896705-16-1]]
• Biozol Catalog Number: FBM-10-5688
• Supplier Catalog Number: 10-5688
• Alternative Catalog Number: FBM-10-5688-5MG,FBM-10-5688-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

RNA polymerase I inhibitor

Product Properties

• Molecular Weight: 360.42
• Purity: >98% by HPLC NMR (Conforms)
• Form: Orange solid
• CAS Number: [896705-16-1]
• Formula: C21H20N4O2

Application Notes

• Application Notes: A planar heterocyclic DNA intercalator that inhibits RNA polymerase I (Pol I), IC50 = 0.6 µM in U2OS cells, but not Pols II or III, blocking transcription elongation without inducing the DNA damage response.1-3 Inhibition disengages Pol I from chromatin,