Human FcRn (FCGRT-B2M) heterodimer protein

Product Overview

• Article Name: Human FcRn (FCGRT-B2M) heterodimer protein
• Biozol Catalog Number: GMP-HUFCRN-U
• Supplier Catalog Number: HUFCRN-U
• Alternative Catalog Number: GMP-HUFCRN-U-1, GMP-HUFCRN-U-5X1
• Manufacturer: Gamma Proteins UK
• Category: Proteine/Peptide
• Application: BLI, ELISA, SBR
• Species Reactivity: Human
• Alternative Names: FcRn, FCGRT, FCGRT & B2M, FCGRT and B2M, Neonatal Fc receptor, Neonatal receptor, Brambell receptor

Product Description

IgG Fc fragment receptor transporter, also known as the neonatal Fc receptor or more commonly FcRn, consist of two subunits (FCGRT and B2M) and forms an MHC class I-like heterodimer. FcRn binds to the Fc domain of monomeric IgG and mediates the pH depend

Product Properties

• Molecular Weight: 46,6 kDa
• UniProt: P55899
• Buffer: PBS, pH7.4
• Source: The sequence of the extracellular domain of human FCGRT (Ala 24-Ser 297) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag. This was co-transfected with the sequence of human B2M (Ile 21-Met 119
• Expression System: HEK293
• Purity: >95 % as determined by SEC-HPLC
• Form: Lyophilized
• Sequence: A24-S297 & I21-M119

Images

Assessment of protein pur